Epidural labor analgesia
Conditions
Interventions
0.0625% Ropivacaine +0.4µg/ml dexmedetomidine with a fixed time interval of 45 minute 6ml group:Injection volume 6ml
0.0625% Ropivacaine +0.4µg/ml dexmedetomidine with a fixed time interval of 45 minute 8ml group:Injection volume 8ml
0.0625% Ropivacaine +0.4µg/ml dexmedetomidine with a fixed time interval of 45 minute 10ml group:Injection volume 10ml
0.0625% Ropivacaine +0.4µg/ml dexmedetomidine with a fixed time interval of 45 minute 12ml group:Injection volume 12ml
Sponsors
Zhejiang Xiaoshan Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) women between the ages of 18 and 40; (2) ASA 2-3 level; (3) gestational age =37 weeks; (4) Cervical dilation 5 (0= no pain, 10= most pain).
Exclusion criteria
Exclusion criteria: (1) intraspinal anesthesia contraindications; (2) Allergic to local anesthetics or dexmedetomidine; (3) bradycardia; (4) refuse to sign the informed consent; (5) Other conditions: history of cesarean section, long-term use of sedatives or analgesics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate for each volume group (6,8,10 or 12ml group).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Each stage of labor time;The use of analgesic pump drugs and the number of patient-controlled compressions;Basic information of maternity;NRS (before analgesia, 30min, 60min, complete uterine opening, fetal delivery).;The basic vital signs and sensory motor block scores of the parturients;Mode of delivery;Side effect;Neonatal Apgar score; | — |
Countries
China
Contacts
Public ContactZhong Mei
Zhejiang Xiaoshan Hospital
Outcome results
None listed