ICU-acquired weakness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Age 18-85 years old; ?Patients with an estimated time of ICU admission > 48 hours; ?Hemodynamics were relatively stable (the dose of vasoactive drugs was not increased within 2 hours); ?Patients with mechanical ventilation: oxygen concentration (FiO2%) < 0.6, positive end-expiratory pressure (PEEP) < 10 cmH2O; ?RASS sedation score =-3 points; ? Lower limb muscle strength greater than grade 3
Exclusion criteria
Exclusion criteria: ? Central nervous system disease and neuromuscular disease were diagnosed before ICU admission; ?Poor functional status (Barthel<45) one week before ICU admission; ? is in the treatment that requires strict control of activity (such as extracorporeal membrane oxygenation and active balloon reperfusion, etc.); ? There are contraindications to activity: such as unstable fracture, orthostatic hypotension; ? Patients with significant irritability or other intolerances to early activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of ICU-AW; | — |
Secondary
| Measure | Time frame |
|---|---|
| General clinical monitoring indicators;Analysis of body muscle and skeletal muscle components;ICU Mobility assessment;Daily activity time; | — |
Countries
China
Contacts
Beijing Friendship Hospital, Capital Medical University,