Chronic Widespread Pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects have to be aged = 18, with the report of musculoskeletal pain in at least 4 of 5 body regions and in at least 3 or more body quadrants (as defined by upper–lower/left–right side of the body) and axial skeleton (neck, back, chest, and abdomen), with pain duration of more than 3 months. A Widespread Pain Index (WPI) will be generated based on the number of pain sites. Subgroup of patients with fibromyalgia will be identified according to The American College of Rheumatology 2016 when subjects have a WPI of = 7 and a symptom severity scale (SSS) score of = 5 or a WPI between 4 and 6 and an SSS score of = 9. The counselling assistant will also perform a one-hour session individually with each of the screened CWP participants to confirm the eligibility of the participants.
Exclusion criteria
Exclusion criteria: Exclusion criteria include major chronic illnesses, such as malignancy, active inflammatory diseases, autoimmune diseases and metabolic diseases such as diabetes mellitus and thyroid diseases, use of antibiotics, probiotics or prebiotics in the preceding 2 months, any acute illness in the preceding month, change in regularly taken medication in the preceding month, and substantial dietary alterations in the preceding month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brief Pain Inventory - Severity score (BPI-S); | — |
Secondary
| Measure | Time frame |
|---|---|
| Brief Pain Inventory - Interference score (BPI-I);Pressure Pain Thresholds, Tender Point Counts, Total Myalgic Score;Kinesiophobia;Physical activity level;Self-efficacy of pain management;Level of anxiety and depression;Fatigue;Overall health-related quality of life; | — |
Countries
China
Contacts
The Chinese University of Hong Kong