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Correlation of non-alcoholic fatty liver disease with cognitive impairment and affective disorders in cerebral small vessel disease

Correlation of non-alcoholic fatty liver disease with cognitive impairment and affective disorders in cerebral small vessel disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081415
Enrollment
Unknown
Registered
2024-02-29
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral small vessel disease

Interventions

no cognitive impairment group:None

Sponsors

The 940 Hospital of Joint Logistics Support Force of Chinese PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. The age range of enrolled participants spans from 35 to 90 years; 2. Patients with CSVD confirmed by cranial CT or MRI, including typical recent small subcortical infarcts, white matter high signal, perivascular gaps, cerebral microhemorrhages, and cerebral atrophy; 3. All subjects underwent abdominal ultrasonography; 4. No antidepressant medications have been utilized in the six months preceding admission; 5. Alcohol consumption is limited to an equivalent of less than 30g/day (males) or less than 20g/day (females); 6. All patients were voluntarily enrolled and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Have speech or hearing impairment and are unable to complete the questionnaire due to communication difficulties; 2. Have severe organ dysfunction (liver and kidney disease), immune diseases, etc.; 3. Have experienced surgery, severe mental trauma, or other mental illness in the past six months Disease patients; 4. Vascular dementia has been confirmed and affects depression scores.

Design outcomes

Primary

MeasureTime frame
moca scale scores;Hamilton Depression Rating Scale scores;Hamilton Anxiety Rating Scale score;Plasma Lipocalin Levels;Plasma Lipocalin Levels;Plasma endolipin levels;Plasma resistin levels;Plasma chemotaxin levels;

Countries

china

Contacts

Public ContactZhao Bo

The 940 Hospital of Joint Logistics Support Force of Chinese PLA

drzhaobo1979@163.com+86 188 9312 4060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026