postoperative pain
Conditions
Interventions
low-volume group :ultrasound-guided bilateral trigeminal nerve block with 0.375% ropivacaine 2 mL (each side)
high-volume group :ultrasound-guided bilateral trigeminal nerve block with 0.375% ropivacaine 5 mL (each side)
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-45 years old. 2. No gender limitation. 3. BMI 18-30 kg/m2. 4. American Society of Anesthesiologists (ASA) physical status classification I–II. 5. Patients undergoing elective bimaxillary orthognathic surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. temporomandibular joint surgery is also required. 2. have any contraindications for controlled hypotension. 3. an established mental illness. 4. inability to communicate due to visual, hearing, speech, or other impairments. 5. Patients with a history of chronic pain or opioid abuse before surgery. 6. allergic to the drug components or ingredients used in this study. 7. have any contraindications for nerve block, including coagulation disorders, infection in the block site, any puncture route related anatomical abnormalities. 8. history of severe bradycardia (heart rate =50 beats per minute); different types of sinoatrial block, Intra-atrial block and intraventricular block; history of morbid sinus node syndrome or pre-excitation syndromes, etc. 9. submental endotracheal intubation was planned rather than transnasal tracheal intubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative visual analogue scale pain score in maxilla; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain assessed at different surgical site;intraoperative hemodynamic changes ;Intraoperative consumption of opioids, sedatives, and vasoactive medication;The use of remedial analgesics within 48h after surgery;the time to first request of analgesia;Postoperative quality of recovery score, QoR-15;nausea;vomiting;Perioperative complications; | — |
Countries
China
Contacts
Public ContactYang Ji
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed