Hand osteoarthritis
Conditions
Interventions
Gold Standard:1) Most of the time in the past month, there has been hand pain, soreness, and stiffness
2) Among the 10 interphalangeal joints, there are = 2 bony enlarged joints
3) Swelling of metacarpophalangeal joints = 2
4) In the distal interphalangeal joint, there are at least 2 deformed joints
5) Among the 10 interphalangeal joints, there is no less than 1 deformed joint.
Index test:Clinical symptom score, VAS score, joint function score, time of morning stiffness before and after treatment, number of joint tenderness, ESR, CRP, blood routine, liver function, renal fun
Sponsors
The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 50-75, regardless of gender, with no reproductive requirements; (2) Those who meet the diagnostic criteria of traditional Chinese medicine and Western medicine for hand osteoarthritis; (3) Severity: Imaging Kellgren Lawrence (K-L) rating = Level II; (4) Visual analog score (VAS) of pain at the time of treatment = 30mm (select the affected limb with the most obvious pain symptoms); (5) 17kg/m2 = body mass index = 30kg/m2 (body mass index BMI=weight (kg)/height (m2)); (6) The patient or their legal representative signs an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals who are allergic to Tripterygium wilfordii glycosides tablets, non-steroidal anti-inflammatory drugs, etc; (2) Body mass index30kg/m2 (body mass index BMI=weight (kg)/height (m2)); (3) Patients with severe cardiovascular and cerebrovascular diseases, lung diseases, hematopoietic system diseases, and liver and kidney dysfunction; (4) Individuals with concomitant mental illness or psychological disorder; (5) Merge with other diseases that may affect the hand bones and joints, such as rheumatoid arthritis, Sjogren's syndrome, gouty arthritis, psoriatic arthritis, etc; (6) Individuals with a history of joint trauma; (7) Pregnant or lactating women under the age of 50 or over 70 years old; (8) Participate in other clinical researchers within 3 months prior to enrollment; (9) There are various other situations where researchers consider it inappropriate to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;Joint function score;Morning stiffness time before and after treatment;Number of joint tenderness;erythrocyte sedimentation Rate;C-reactive protein;X—ray; | — |
Countries
China
Contacts
Public ContactYang Xiaoyu
The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Outcome results
None listed