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Effect of flow-optimized pressure-controlled Volume-assured ventilation mode (PCV-VG) on postoperative pulmonary complications in patients with single lung ventilation: a randomized controlled study

Effect of flow-optimized pressure-controlled Volume-assured ventilation mode (PCV-VG) on postoperative pulmonary complications in patients with single lung ventilation: a randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081358
Enrollment
Unknown
Registered
2024-02-29
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary disease

Interventions

Experimental group:The tidal volume of two-lung ventilation was 8ml /kg, the tidal volume of single-lung ventilation was 6ml/kg, the positive end-expiratory pressure (PEEP) was 5cmH2O, the partial end
Control group:The tidal volume of two-lung ventilation is 8ml /kg, the tidal volume of single-lung ventilation is 6ml/kg, the flow rate of fresh air is 2L/min, the positive end-expiratory pressure (PE

Sponsors

The First People's Hospital of Shuangliu District ,Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? For adult patients scheduled for selective pulmonary resection (segmentectomy, lobectomy, bilobectomy, sleeve lobectomy, pulmonary resection), single lung ventilation time is expected to be =30min; ?Age =19 years old, ASAI-III grade; ? Agree to participate in this study, have signed the informed consent; ?The patient has no history of mental illness (depression, schizophrenia), drug abuse and alcoholism; ? did not participate in other studies;

Exclusion criteria

Exclusion criteria: ? Heart failure; ? Pulmonary bulla, emphysema; ? Pregnant and lactating women; ? Oxygen therapy;?Extra-pulmonary surgery; ? Refuse to participate in this test; ? Other major diseases, can not tolerate surgery.

Design outcomes

Primary

MeasureTime frame
Atelectasis immediately after surgery;

Secondary

MeasureTime frame
Postoperative pulmonary complications;Peak airway pressure;Airway plateau pressure;Dynamic lung compliance;Respiratory rate;Oxygen absorption concentration;Oxygenation index;

Countries

China

Contacts

Public ContactZhang Gongwei

The First People's Hospital of Shuangliu District, Chengdu

467667920@qq.com+86 180 1159 4651

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026