fulminant myocarditis
Conditions
Interventions
control group:Routine treatment of fulminant myocarditis with medication and physiological saline. 50ml physiological saline, intravenous drip, once a day, medication duration: 10 ± 3 days.
Test group:Routine treatment for fulminant myocarditis plus injection of coenzyme I. Co enzyme I for injection, 50mg per dose (powder injection, 5mg per dose), prepared with 50ml physiological saline,
Sponsors
Tongji Hospital, Tongji Medical College,
Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: According to the diagnostic reference standards agreed upon by Chinese experts in the diagnosis and treatment of adult fulminant myocarditis in 2017, patients diagnosed with fulminant myocarditis
Exclusion criteria
Exclusion criteria: 1) Pregnant or recently pregnant women, lactating women; 2) Coenzyme I, lactose intolerance or lactose allergy; 3) Secondary or primary unconsciousness, cognitive impairment, or abnormal mental behavior; 4) Individuals with a history of severe allergies or infusion reactions in the past; 5) Patients with severe liver and kidney dysfunction: ALT or AST>5 times the upper limit, glomerular filtration rate = 30mL/min/1.73 ?; 6) Engaging in clinical research on other drugs; 7) In addition to the above, the researchers have determined that there are other reasons why it is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cTnl; | — |
Secondary
| Measure | Time frame |
|---|---|
| echocardiography;NT-pro BNP;electrocardiogram; | — |
Countries
China
Contacts
Public ContactDaowen Wang
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed