Congenital heart disease
Conditions
Interventions
Observers:All children included in the study were monitored by NIRS for SctO2,
Sponsors
Fujian Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 12 Years
Inclusion criteria
Inclusion criteria: 1.Children undergoing radical operation of congenital heart disease under general anesthesia and cardiopulmonary bypass; 2. Under 12 years of age; 3. General clinical data such as age, sex, weight and anesthesia grade are complete; 4. The family members of the children were informed about this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Combined with chromosome diseases, genetic metabolic diseases, malignant tumors or other congenital diseases; 2. Recently complicated with major surgery history of other systems; 3. Combined with other congenital malformations; 4. Combined with spontaneous intracerebral hemorrhage or brain injury; 5. Combined cerebral palsy;6. Secondary heart surgery;7. Seriously affect the malnutrition or other children who do not meet the surgical conditions;8.Severe cyanosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Third-generation pediatric death hazard score at 24 hours after surgery;Maximum vasoactive drug index at 24 hours after surgery;Mechanical ventilation time;Time in ICU;Serious complications;Other indicators, including the age of surgery, surgical weight, highest lactate value 24 hours after surgery, highest blood glucose value, hospital stay, etc; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory cytokines;Indicators of heart injury;Indicators of brain injury;Indicators of kidney injury; | — |
Countries
China
Contacts
Public ContactZengchun Wang
Fujian Children's Hospital
Outcome results
None listed