Withdraw due to duplicate registration. Application of trans-nasal humidified rapid insufflation ventilatory exchange during the induction period of general anesthesia in emergency surgical patients with traumatic brain injury

Application of transnasal humidified rapid-insufflation ventilatory exchange technology in patients undergoing surgery with different degrees of traumatic brain injury during the induction period of general anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400081339

Enrollment

Unknown

Registered

2024-02-28

Start date

2023-03-15

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic brain injury

Interventions

H group:Transnasal humidified rapid-insufflation ventilatory exchange technology

C group:Routine mask ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing general anesthesia surgery for acute TBI; (2) Age= 18 years old; (3) Eligible for HFNC oxygen therapy: normal spontaneous breathing, and airway patency; (4) Male or female

Exclusion criteria

Exclusion criteria: (1) ASA > IVE; (2) previous history of esophageal lesions and gastric surgery; (3) Have a history of nasal mucosal lesions, nasal surgery and trauma; (4) With the endotracheal tube into the operating room; (5) Poor postoperative outcome.

Design outcomes

Primary

Measure	Time frame
Regional Cerebral Oxygen Saturation;	—

Secondary

Measure	Time frame
The distal cross-sectional area;Optic nerve sheath diameter;For the first time to exhale during mechanical ventilation at the end of the co2 partial pressure;The incidence of hypoxemia during intubation;Residence time in the ICU;The hospitalization time;	—

Countries

China

Contacts

Public ContactGao Ju

Subei People's Hospital

gaoju_300@qq.com+86 180 5106 3988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026