Spinal infection
Conditions
Interventions
Gold Standard:pathological examination
Interferon-gamma Release Tests (IGRA)
Real-time fluorescence quantitative amplification and nucleic acid amplification for detection of rifampicin resistance(X-pert)
Microculture
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: (1) Imaging and serological examination indicated spinal infection, and CT/ X-ray guided needle biopsy or open spinal surgery was planned. (2) Age: =80 years old (3) Gender: male or female (4) those who signed the informed consent form
Exclusion criteria
Exclusion criteria: (1) Participants who had participated in other clinical trials within 4 weeks before the start of the study (2) patients without infection indicated by postoperative pathological examination and pathogenic examination (3) patients who failed to come to the hospital for reexamination at the prescribed time (4) patients with abnormal immune function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markers;Imageological examination;Interferon-gamma Release Tests;sensitivity;specificity;positive predicative value;negative predicative value; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic and renal function;coagulation function;body mass index; | — |
Countries
China
Contacts
Public ContactQile Gao
Xiangya Hospital, Central South University
Outcome results
None listed