Medical abortion
Conditions
Interventions
Study group:Oral administration of Gongxuening capsules on the same day after medical abortion, 3 times a day, 2 capsules each time, for 9 consecutive days
Control group:Oral placebo capsules, 3 times a day, 2 capsules each time, taken continuously for 9 days
Sponsors
Women's Hospital School Of Medicine Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 18 years old = Age = 40 years old; Patients who have an intrauterine pregnancy of = 7 weeks (49 days) and a gestational sac diameter of = 25 mm and are required to terminate the pregnancy without contraindications and undergo medical abortion; Patients who meet the criteria for medical abortion according to the Clinical Diagnosis and Treatment Guidelines and Technical Operation Standards: Family Planning Volume (2017 Revised Edition) (need to undergo examinations such as vaginal secretions, blood routine [reimbursement], coagulation function [reimbursement], liver and kidney function [reimbursement], electrocardiogram, and three-dimensional ultrasound of the uterine appendages [reimbursement]); Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: Patients who have failed to use emergency contraceptive pills for contraception; Patients with accompanying mental state, cognitive dysfunction, and inability to cooperate with the treatment process; Patients with gastrointestinal dysfunction; Patients who have a need for oral contraceptives or intrauterine devices (IUDs) within 3 months after medical abortion; Other situations that the researcher determines are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal bleeding volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of incomplete abortion;Blood stasis time (days);Menstrual recovery time (days);Endometrial thickness (mm) [Note: Double layer];Uterine spiral artery hemodynamic levels: PI arterial pulse (peak systolic velocity, cm/s), VI (vascular index), VFI (vascular flow index) [note: bilateral];Serum sex hormone levels: estradiol (E2, pmol/L), pituitary prolactin (PRL, ng/ml), progesterone (P, nmol/L), luteinizing hormone (LH, IU/L), and follicle stimulating hormone (FSH, IU/L); | — |
Countries
China
Contacts
Public ContactXiuxiu Jiang
Women's Hospital School of Medicine Zhejiang University
Outcome results
None listed