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Effect of different vasoactive drug premedication on hemodynamics during induction of general anesthesia in elderly patients with sarcopenia

Effect of different vasoactive drug premedication on hemodynamics during induction of general anesthesia in elderly patients with sarcopenia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081301
Enrollment
Unknown
Registered
2024-02-28
Start date
2023-12-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Interventions

Group B:Pumped norepinephrine was given at the same time as induction
Group C:Ephedrine was given at the same time as induction
Group A:Saline was given at the same time as induction

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Voluntary informed consent; (2) 65 years old and above; (3) Patients with ASA I~III; (4) Planning elective surgery under general anesthesia; (5) Meeting diagnostic criteria for sarcopenia.

Exclusion criteria

Exclusion criteria: (1) Preoperative subjects with severe cardiorespiratory abnormalities, thyrotoxicosis, cardiovascular disease, history of cardiac arrhythmias, and presence of other hepatic and renal diseases; (2) Preoperative systolic (SAP) or diastolic (DAP) arterial blood pressure greater than 200 mmHg and 110 mmHg, respectively; (3) Sudden and severe perioperative complications; (4) Difficult airway.

Design outcomes

Primary

MeasureTime frame
Blood pressure;Incidence of hypotension;End-expiratory carbon dioxide;Postoperative Awakening Status;

Secondary

MeasureTime frame
Heart rate;Arterial blood gas analysis;Pulse Oximetry Saturation;

Countries

China

Contacts

Public ContactZaisheng Qin

Nanfang Hospital, Southern Medical University

QZSMZK@163.com+86 134 3424 3868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026