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Explore the correlation between body composition characteristics and the gut microbiota in sarcopenia based on the theory of "spleen governing muscles".

Explore the correlation between body composition characteristics and the gut microbiota in sarcopenia based on the theory of "spleen governing muscles".

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081281
Enrollment
Unknown
Registered
2024-02-28
Start date
2024-02-28
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia

Interventions

sarcopenia with faint physical group
:none
sarcopenia with mild physical group
non-sarcopenia with faint physical group
non-sarcopenia with mild physical group

Sponsors

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 83 Years

Inclusion criteria

Inclusion criteria: ? Aged 60~84 years old who meet the diagnostic criteria of sarcopenia and the diagnosis of qi deficiency or peace quality; Or age 60~84 Aged people who met the Qi-deficiency quality but did not meet the diagnosis of sarcopenia. ? Can cooperate with the completion of body composition analysis, grip strength measurement, 6m walking time measurement and questionnaire. ? No drugs that directly affect intestinal flora, such as antibiotics and probiotics, have been taken within 2 weeks before the collection of stool samples Other drugs for the digestive tract. ? Agree to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? Patients with diseases that seriously affect muscle and bone metabolism, such as malignant tumors, cerebrovascular accidents, severe liver disease, severe kidney disease, severe diabetes, thyroid disease, parathyroid disease, nervous system disease, etc. ? Patients with severe neck, waist and knee diseases, affecting standing and walking and grip strength test; ? Patients with acute and chronic gastroenteritis and other digestive diseases; (4) Drugs affecting intestinal flora, such as antibiotics, probiotics and other drugs used in the digestive tract, have been taken within 2 weeks before collecting stool samples. ? With severe mental illness or cognitive impairment (simple intelligence scale score less than 20 points), can not cooperate with the questionnaire respondents.

Design outcomes

Primary

MeasureTime frame
Upper limb muscle mass;Lower limb muscle mass;Trunk muscle mass;Total limb muscle mass;

Secondary

MeasureTime frame
score of SPPB scale;time spent on five sit up tests;6-meter walking speed;the power of gripping;

Countries

China

Contacts

Public ContactLi Bin

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine

libin@cdutcm.edu.cn+86 158 8246 3615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026