Chemotherapy induced peripheral neuropathy
Conditions
Interventions
Sponsors
Tianjin Cancer Hospital Airport Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with malignant tumors through pathology or cytology; 2) Age range from 18 to 80 years old, regardless of gender; 3) Expected survival time = 3 months; 4) Individuals who have developed CIPN symptoms after receiving chemotherapy with neurotoxic drugs such as platinum, paclitaxel, vinblastine, bortezomib, and thalidomide, and those with NCI grade I or above neuropathic symptoms; 5) Patients without strict center of gravity, kidney, liver, lung, or hematopoietic system dysfunction; 6) Clear consciousness, able to communicate normally, able to cooperate with medical staff to complete questionnaire surveys, physical examinations and evaluations; 7) Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Expected survival time<3 months; 2) Patients with neurological compression symptoms caused by secondary tumors caused by brain metastasis or other; 3) Patients with multiple organ failure caused by neurological disorders such as poisoning, infection, radiation therapy, or other reasons; 4) Neuropathy caused by diabetes peripheral neuropathy or other self basic diseases; 5) Individuals with severe liver and kidney dysfunction, cardiovascular and cerebrovascular diseases, or other serious complications; 6) Unsigned informed consent form; 7) Patients undergoing treatment with other drugs that may cause neurotoxicity; 8) Patients with symptomatic and difficult to control neurological, psychiatric, or psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EORTC QLQ-CIPN20 Neurotoxicity Evaluation Criteria; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life score(EORTC QLQ-C30); | — |
Countries
China
Contacts
Public ContactZhuchen Yan
Tianjin Cancer Hospital Airport Hospital
Outcome results
None listed