Simple vascular / lymphatic vessel malformation
Conditions
Interventions
Group 3-6 years:Including children aged 3-6 years old, the anesthesiologist and family members work together to adjust the child's position so that the child is in a supine position with his head tilt
Group 7-12 years:Including children aged 7-12 years old, the anesthesiologist and family members work together to adjust the child's position so that the child is in a supine position with his head ti
Group 13-18 years:Including children aged 13-18 years old, the anesthesiologist and family members work together to adjust the child's position so that the child is in a supine position with his head
Sponsors
Guangzhou Medical University Affiliated Women and Children's Medical Center
Eligibility
Sex/Gender
All
Age
3 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children with simple vascular/lymphatic malformations classified according to the International Society for the Study of Vascular Malformations (Milwaukee, WI) standard classification and requiring interventional surgery under general anesthesia; 2.Age 3-18 years old; The American Society of Anesthesiologists (ASA) assessment level is level I-III;
Exclusion criteria
Exclusion criteria: 1. Premature infants or children with severe growth and development delay; 2. Have a history of allergy or hypersensitivity to dexmedetomidine; 3. Severe heart, liver, and kidney dysfunction; 4. Have used dexmedetomidine or any other sedative within one week; 5. Active respiratory symptoms, runny nose, vascular malformation and other symptoms in or near the nasal cavity that may affect nasal drug absorption; 6. Nose bleeding, history of sinus surgery and severe nasal septum deviation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pharmacokinetic parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to wake up ;Incidence of adverse events; | — |
Countries
China
Contacts
Public ContactBilian Li
Guangzhou Women and Children's Medical Center
Outcome results
None listed