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Application of CT to bone-muscle-fat-vascular axis in type 2 diabetes mellitus

Application of CT to bone-muscle-fat-vascular axis in type 2 diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081243
Enrollment
Unknown
Registered
2024-02-27
Start date
2023-06-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes Mellitus

Interventions

case serise (Part One: The application of CT to study the relationship between arterial calcification and perivascular fat in type 2 diabetes mellitus):No
case serise (Part Two: Study on the effect of CT on muscle, bone and fat in type 2 diabetes mellitus):No
case serise (Part Three: Quantitative analysis of bone mineral density and coronary artery calcification with CT in type 2 diabetes mellitus):No

Sponsors

Radiology Center, the First Affiliated Hospital of the University of South China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Age 18 years old; Type 2 diabetes was diagnosed according to WHO diagnostic criteria; ? Chest and abdominal CT scans were performed in serial scan mode at baseline examination; ? Be able to understand the purpose and procedure of this study.

Exclusion criteria

Exclusion criteria: ? had received or planned arterial surgery; ? Patients with severe lung (respiratory failure), liver (ALT or AST 3 times normal and bilirubin elevated), kidney (GFR < 45ml/min/1.73m2 or dialysis patients) dysfunction; ? Malignant tumor; Pregnant or lactating women or those who have a family plan; (5) concomitant diseases affecting calcium balance and soft tissue calcification (hyperparathyroidism, sarcoidosis, amyloidosis); ? The researcher judged that the compliance was poor and the study could not be completed as required.

Design outcomes

Primary

MeasureTime frame
Density of periaortic adipose tissue (the primary indicator of part one);Volume of periaortic adipose tissue (the primary indicator of part one);Bone mineral density (the primary indicator of part two and three);Aortic calcification scores (the primary indicator of part one);Coronary calcification scores (the primary indicator of part three);Area of chest and abdominal muscles (the primary indicator of part two);Density of chest and abdominal muscles (the primary indicator of part two);Density of chest and abdominal fat(the primary indicator of part two);Area of chest and abdominal fat(the primary indicator of part two);

Countries

China

Contacts

Public ContactZhao Heng

Radiology Center, the First Affiliated Hospital of the University of South China

angerh9@126.com+86 189 7473 5009

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026