hyperTriglyceridemic Acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age range from 18 to 70 years old; (2) AP onset time = 48 hours; (3) Meets the diagnostic criteria for hypertriglyceridemic Acute pancreatitis; (4) Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who have undergone pancreatic surgery in the past; (2) Pregnant or lactating women; (3) Acute progression of chronic pancreatitis; (4) Chronic obstructive pulmonary disease (COPD) patients with severe heart, lung, liver, kidney, and mental illnesses that affect the treatment effect of acute pancreatitis or cannot cooperate with the operator (NYHA grade>III, acute myocardial infarction, chronic kidney disease with creatinine clearance rate<40ml/min, requiring long-term oxygen therapy, Child Pugh C grade liver function in chronic liver disease, immune disease or immunosuppressive status, and dying patients); (5) Individuals who cannot tolerate ERCP for various reasons (such as contrast agent allergies, severe gastroesophageal varices; upper gastrointestinal obstruction, ulcers, bleeding, etc.; coagulation dysfunction or long-term oral anticoagulant medication; patient or family member refusal, etc.); (6) Individuals who need to take pancreatic toxic drugs (such as estrogen, azathioprine, mesalazine, morphine derivatives, and prednisone) during the study period; (7) Patients with combined biliary and pancreatic system tumors that affect treatment effectiveness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of persistent or new onset organ failure;Length of hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score;Incidence of complications;Intervention rate;Mortality;ICU treatment rate;Changes in laboratory indicators;Dosage of painkillers;Changes in daily APACHE-II score/improved Marshall score/SOFA score;Oral re-feeding time;Application of pancreatic enzyme inhibiting drugs;Expenses incurred during treatment; | — |
Countries
China
Contacts
General Hospital of Ningxia Medical University