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Research on clinical efficacy of Emergency pancreatic duct Stenting in the treatment of hyperTriglyceridemic Acute pancreatitis (ESAT)

Research on clinical efficacy of Emergency pancreatic duct Stenting in the treatment of hyperTriglyceridemic Acute pancreatitis (ESAT) - ESAT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081236
Enrollment
Unknown
Registered
2024-02-27
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperTriglyceridemic Acute pancreatitis

Interventions

pancreatic duct stent:pancreatic duct stenting

Sponsors

General Hospital of Ningxia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age range from 18 to 70 years old; (2) AP onset time = 48 hours; (3) Meets the diagnostic criteria for hypertriglyceridemic Acute pancreatitis; (4) Voluntarily participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients who have undergone pancreatic surgery in the past; (2) Pregnant or lactating women; (3) Acute progression of chronic pancreatitis; (4) Chronic obstructive pulmonary disease (COPD) patients with severe heart, lung, liver, kidney, and mental illnesses that affect the treatment effect of acute pancreatitis or cannot cooperate with the operator (NYHA grade>III, acute myocardial infarction, chronic kidney disease with creatinine clearance rate<40ml/min, requiring long-term oxygen therapy, Child Pugh C grade liver function in chronic liver disease, immune disease or immunosuppressive status, and dying patients); (5) Individuals who cannot tolerate ERCP for various reasons (such as contrast agent allergies, severe gastroesophageal varices; upper gastrointestinal obstruction, ulcers, bleeding, etc.; coagulation dysfunction or long-term oral anticoagulant medication; patient or family member refusal, etc.); (6) Individuals who need to take pancreatic toxic drugs (such as estrogen, azathioprine, mesalazine, morphine derivatives, and prednisone) during the study period; (7) Patients with combined biliary and pancreatic system tumors that affect treatment effectiveness.

Design outcomes

Primary

MeasureTime frame
The incidence of persistent or new onset organ failure;Length of hospital stay;

Secondary

MeasureTime frame
Pain score;Incidence of complications;Intervention rate;Mortality;ICU treatment rate;Changes in laboratory indicators;Dosage of painkillers;Changes in daily APACHE-II score/improved Marshall score/SOFA score;Oral re-feeding time;Application of pancreatic enzyme inhibiting drugs;Expenses incurred during treatment;

Countries

China

Contacts

Public ContactYao Weijie

General Hospital of Ningxia Medical University

ayaoataq@sina.com+86 177 9511 2972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026