Diaphragm dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) ASA Grade I-?; (2) Aged between 18 and 80; (3) Cardiac function grade I ~ ?; (4) Airway intubation and mechanical ventilation; (5) The ability to breathe spontaneously, cough and expectorate, with little airway secretion; (6) Clear mind, no sedative drugs used; (7) Hemodynamic stability without the need for vasoactive drugs.
Exclusion criteria
Exclusion criteria: (1) A history of thoracic organ surgery; (2) A history of pulmonary disease; (3) Thoracic deformity, pleuroceliac effusion or huge tumor; (4) A history of diaphragmatic dysfunction; (5) Serious heart and lung diseases and liver and kidney insufficiency; (6) Patients allergic to anesthetic drugs, muscle relaxants and antagonists; (7) Blood gas PaO2/FiO2<300mmHg before surgery or SpO2 lower than 93% at home; (8) Patients who cannot cooperate with doctors for ultrasound examination; (9) Patients or family members refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragmatic thickness;Diaphragmatic excursion;Oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of operation;Extubation time;BMI;ASA classification;Fluid intake and outflow (including urine and bleeding); | — |
Countries
China
Contacts
Department of Anesthesiology, the Second Affiliated Hospital of Chongqing Medical University