none
Conditions
Interventions
3-6 age group:30 minutes before MRI examination, dexmedetomidine (3 µg/kg) was given intranasally. Remimazolam was then given intravenously before MRI examination. The dose of remimazolam was determin
1-3 age group:30 minutes before MRI examination, dexmedetomidine (3 µg/kg) was given intranasally. Remimazolam was then given intravenously before MRI examination. The dose of remimazolam was determin
3 month-1 age group:30 minutes before MRI examination, dexmedetomidine (3 µg/kg) was given intranasally. Remimazolam was then given intravenously before MRI examination. The dose of remimazolam was de
Sponsors
Guangzhou Women and Children’s Medical Center, Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
0.3 Years to 6 Years
Inclusion criteria
Inclusion criteria: The hospitalized children who required sedation during magnetic resonance imaging (MRI) were enrolled. The examination time was expected to be less than 1 hour, and the age between 3 months and 6 years old with an American Standards Association physical status of I–III.
Exclusion criteria
Exclusion criteria: History of anaphylaxis to anesthetics, unstable vital signs, severe heart and lung diseases, severe liver and kidney dysfunction, upper respiratory tract infection, severe sleep apnea syndrome or other airway obstructive diseases, use of sedatives within 48 hours before examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sedation results of remimazolam;dose of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of rescue sedation drugs during induction;Use of sedation drugs during examination;Blood pressure;Heart rate;Oxygen saturation; | — |
Countries
China
Contacts
Public ContactWanjun Zheng
Guangzhou Women and Children’s Medical Center, Guangzhou Medical University
Outcome results
None listed