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Study on the correlation between intestinal flora and its metabolites and cognitive impairment in patients with AVS

Study on the correlation between intestinal flora and its metabolites and cognitive impairment in patients with AVS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081198
Enrollment
Unknown
Registered
2024-02-26
Start date
2024-02-28
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic valve stenosis

Interventions

Cognitive impairment group (observation group) and non cognitive impairment group (control group):NA

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Patients with AVS were diagnosed by ultrasound; ? Age =18 years old; ? Patients and their family members agreed to participate in the study voluntarily.

Exclusion criteria

Exclusion criteria: ? Patients with other heart diseases, neuropsychiatric diseases, organic brain diseases, metabolic or endocrine diseases have not been effectively controlled; ? Visual impairment/color blindness unable to complete the cognitive assessment; ? Patients who took antibiotics, probiotics or prebiotics within two months before admission; ? Severe malnutrition, infection, drug or alcohol abuse, irritable bowel syndrome, and inflammatory bowel disease in the last 1 year.

Design outcomes

Primary

MeasureTime frame
gut microbiota; short chain fatty acid;trimethylamino oxide;

Secondary

MeasureTime frame
inflammatory factor;

Countries

China

Contacts

Public ContactLin Yanjuan

Fujian Medical University Union Hospital

fjxhyjl@163.com+86 591 8621 8336

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026