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The differences in frontal lobe electroencephalogram between propofol and sevoflurane anesthesia in children:A prospective, randomized, controlled study

The differences in frontal lobe electroencephalogram between propofol and sevoflurane anesthesia in children:A prospective, randomized, controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081194
Enrollment
Unknown
Registered
2024-02-26
Start date
2024-02-29
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium during recovery from general anesthesia

Interventions

Propofol group :Anesthesia was induced and maintained with propofol
Sevoflurane group:Anesthesia was induced and maintained with sevoflurane

Sponsors

Department of Anesthesia and Perioperative Medicine, the First Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1) Age: 3-6 years old;2)ASA I-II;3) children undergoing elective ENT surgery under general anesthesia;4) The guardian signed the informed consent

Exclusion criteria

Exclusion criteria: 1) use of psychotropic or analgesic drugs within one month before surgery;2) those with forehead skin damage or scar are not suitable for intraoperative EEG signal acquisition;3) children with cardiovascular disease, liver and kidney dysfunction, neuropsychiatric disorders, and hearing impairment;4) children who plan to be admitted to the intensive care unit after surgery;5) Expected operation time < 1h

Design outcomes

Primary

MeasureTime frame
d relative power (dRP) during awakening from anesthesia;

Secondary

MeasureTime frame
Other wave RP during emergence phases;d-a ratio (DAR);LF/HF ratio;Emergence time (the time between drug withdrawal and discharge from the operating room);Eye opening time (the time from drug withdrawal to eye opening or response to call);PAED scale and FLACC scale score scores;Incidence of delirium during emergence from general anesthesia;

Countries

China

Contacts

Public ContactHaixing Zhong

Department of Anesthesia and Perioperative Medicine, the First Affiliated Hospital of Air Force Medical University

Haixing.zhong@139.com+86 139 9194 6615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026