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A Study on the Mechanisms Related to Rebound pain After Peripheral Nerve Block

A Study on the Mechanisms Related to Rebound pain After Peripheral Nerve Block

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081153
Enrollment
Unknown
Registered
2024-02-23
Start date
2024-04-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rebound pain after peripheral nerve block

Interventions

Observation group:None

Sponsors

Xiangyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.The orthopedic surgery patients in Xiangyang Central Hospital between 2024/03/01 to 2024/09/30; 2.Aged 18-75 years old; 3.ASA I-III grade; 4.Intend to undergo internal fixation of unilateral upper limb fracture (humerus and below) under brachial plexus block (intermuscular sulcus+axillary route);

Exclusion criteria

Exclusion criteria: 1. patients with concomitant surgery at other sites; 2. emergency surgery; 3. peripheral neuropathy, preoperative upper limb with nerve injury; 4. previous axillary surgery on the surgical side; 5. multiple operations on the surgical side of the upper limb(>1 time); 6. patients with local anesthetic allergy and contraindications for postoperative analgesics (such as NSAID and paracetamol); 7. pregnant women; 8. patients with diabetes and vascular diseases; 9. long-term use of opioids, antipsychotics and antidepressants; 10. injection site infection, acute porphyria or nephropathy requiring dialysis; 11. contraindications to regional anesthesia, patients with general anesthesia and nerve block insufficiency assisted general anesthesia or changed general anesthesia; 12. patients with chronic pain syndrome; 13. patients who could not understand the perioperative questionnaire (language problems or cognitive impairment); 14. participated in similar studies in the past three months;

Design outcomes

Primary

MeasureTime frame
numerical rating scale of pain;

Secondary

MeasureTime frame
visual analogue of anxiety;headache, dizziness, nausea, vomiting;postoperative analgesics usage;

Countries

China

Contacts

Public ContactXingrui Gong

Xiangyang Central Hospital

40415311@qq.com+86 15071551981

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026