Median open heart surgery
Conditions
Interventions
Control group:No PIFB will be performed. Intravenous analgesia pump (PCIA) will be used after surgery. The drug formula is Sufentanil 2.5µg/kg+ esketamine 1mg/kg+ dexmedetomidine 2.5ug/kg, diluted to
Pectointercostal fascial block with a constant basal infusion:On the basis of the general anesthesia group, bilateral thoracic intercostal fascia block was added, 0.375% ropivacaine 20 ml was injected
Pectointercostal fascial block with a automated intermittent boluses infusion:On the basis of the general anesthesia group, bilateral thoracic intercostal fascia block was added, 0.375% ropivacaine 2
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Patients =18 years of age undergoing elective classical open-heart surgery.
Exclusion criteria
Exclusion criteria: 1. Patients and their families refused to participate in the study; 2. Allergic to amide local anesthetics; 3. Patients who are unable to carry out normal communication and evaluation due to factors such as language impairment, hearing impairment, and mental illness; 4. Patients with grade IV heart function; 5. Pre-existing neurological disease; 6. Preoperative coagulation dysfunction; 7. Patients with infection in the puncture and catheter indwelling area; 8. People with sepsis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sufentanil consumption;Resting and dynamic VAS scores after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24h, 48h, 72hQoR-15 scores after extubation;IL-6, IL-10, TNF-a levels;Mechanical ventilation time;ICU stay time;Time to get out of bed;Recovery time of gastrointestinal function;Incidence of postoperative delirium;Incidence of postoperative chronic pain;Incidence of postoperative chronic pain;The incidence of other postoperative complications; | — |
Countries
China
Contacts
Public ContactZhi Ye
Xiangya Hospital, Central South University
Outcome results
None listed