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Enhancing Oxygenation Efficiency in Rigid Bronchoscopy: A Feasibility Study of Jet Ventilation with Supplementary Oxygen

Enhancing Oxygenation Efficiency in Rigid Bronchoscopy: A Feasibility Study of Jet Ventilation with Supplementary Oxygen

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081138
Enrollment
Unknown
Registered
2024-02-23
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transbronchial needle aspiration biopsy (TBNA) guided by endobronchial ultrasound (EBUS)

Interventions

Experimental group 1:After the induction of general anesthesia, a rigid bronchoscope was inserted. The ventilatory parameters were set as follows: a respiratory rate (RR) of 15 breaths per minute and
Experimental group 2:After the induction of general anesthesia, a rigid bronchoscope was inserted. The ventilatory parameters were set as follows: a respiratory rate (RR) of 15 breaths per minute and
Control group:After the induction of general anesthesia, a rigid bronchoscope was inserted. The ventilatory parameters were set as follows: a respiratory rate (RR) of 15 breaths per minute and an insp

Sponsors

The Second Affiliated Hospital of Xiamen Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: This study included patients who underwent rigid bronchoscopic surgery, conforming to pertinent diagnostic investigations. All participants provided signed informed consent and demonstrated active cooperation with the study. The age range of the patients was 18 to 75 years, with an American Society of Anesthesiologists (ASA) classification of II to III."

Exclusion criteria

Exclusion criteria: Exclusion criteria for the study consisted of: 1) patients contraindicated for surgery, 2) patients in the acute phase of Chronic Obstructive Pulmonary Disease (COPD), acute asthma, or pulmonary infection, 3) patients with severe cardiovascular diseases, and 4) patients unwilling or unable to participate in the study."

Design outcomes

Primary

MeasureTime frame
arterial oxygen partial pressure;arterial carbon dioxide pressure;Vital signs;driving pressure (DP);Arterial blood lactic acid value;

Secondary

MeasureTime frame
Awakening score;clinical pulmonary infection score;tumor necrotic factor a (TNF-a);Interleukin-1 ß (IL-1ß);Interleukin-6 (IL-6);Operation time;Arterial blood PH value;

Countries

China

Contacts

Public ContactJian-Liang Peng

The Second Affiliated Hospital of Xiamen Medical College

pjl2023@xmmc.edu.cn+86 136 4602 5192

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026