Effects of acupoint application combined with auricular acupressure on depression in stroke patients: a resting-state functional magnetic resonance imaging study

Application Research on Poststroke Depression Rehabilitation Based on Central Response Characteristics of Acupoint Effects

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400081129

Enrollment

Unknown

Registered

2024-02-23

Start date

2023-05-09

Completion date

Unknown

Last updated

2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke depression

Interventions

blank group:basic treatment

control group:basic treatment + sham auricular acupressure + sham acupoint application

auricular acupressure group:basic treatment + auricular acupressure + sham acupoint application

acupoint application group:basic treatment + sham auricular acupressure + acupoint application

acupoint application combined with auricular acupressure group:basic treatment + auricular acupressure + acupoint application

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Clear consciousness and good cooperation; (2) older than 18 but younger than 75 years; (3) a score of 17 or higher on the 17-item Hamilton Rating Scale for Depression (HAMD-17); (4) diagnosed with PSD by the diagnostic criteria for depression of Chinese Classification and Diagnostic Criteria for Mental Disorders (3rd edition, CCMD-3); (5) junior high school education or above; (6) not taking any antidepressant medication within 2 weeks before admission and not participating in other clinical studies; (7) no history of psychiatric disorders or insomnia; and (8) signed an informed consent form to voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: (1) Severe cognitive dysfunction; (2) dysphasia or aphasia; (3) serious dysfunction of important organs like heart, lung, liver and kidney; (4) presence of another chronic disorder, including severe Parkinson's disease, cancer, epilepsy, or chronic alcoholism; (5) having eczema, ulcer and frostbite in the external ear; (6) allergy and intolerance to drugs; (7) receiving other psychological intervention methods; and (8) refusing to complete the intervention session.

Design outcomes

Primary

Measure	Time frame
regional homogeneity (ReHo);	—

Secondary

Measure	Time frame
Hamilton Depression Scale;quality of life;Self-rating Depression Scale;	—

Countries

China

Contacts

Public ContactXiaojun Yin

Zhejiang Provincial People's Hospital

yxj3913@163.com+86 159 2561 2368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026