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Efficacy and safety analysis of 5% POvidone-iodine wiping disinfection of conjunctival sac before cataract surgery

Efficacy and safety analysis of 5% POvidone-iodine wiping disinfection of conjunctival sac before cataract surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081114
Enrollment
Unknown
Registered
2024-02-22
Start date
2024-02-22
Completion date
Unknown
Last updated
2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract

Interventions

Group A: 5%PVI conjunctival sac irrigation for 30s:conjunctival sac irrigation 30s
Group B: 5%PVI conjunctival sac irrigation for 3min:conjunctival sac irrigation for 3min
Group C: 5%PVI conjunctival sac wipe 30s:conjunctival sac wipe 30s
Group D: 5%PVI conjunctival sac wipe 3min: conjunctival sac wipe 3min

Sponsors

West China Hospital,Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: a. Patients aged 50-80 years who plan to undergo cataract surgery for both eyes within one month, male or female b. Patients diagnosed with senile cataract c. No chronic diseases such as hypertension or diabetes d. No acute or chronic infectious diseases of the eye

Exclusion criteria

Exclusion criteria: a. People who are allergic to PVI b. History of eye surgery or eye trauma within the last three months c. Rule out glaucoma, fundus diseases, or other eye diseases combined with corneal and conjunctival diseases d. History of eye medication and contact lens wearing in the past month

Design outcomes

Primary

MeasureTime frame
Positive rate of bacteria culture in conjunctival sac;Whether there is residual secretion on the ocular surface before and after disinfection;The occurrence of endophthalmitis;

Secondary

MeasureTime frame
OSDI scale;Eyelids have redness, swelling and itching;Evaluation of conjunctival congestion;BUT ;Corneal fluorescein staining;Tear secretion test;Evaluation of meibomian glands;Corneal endothelial cell count and morphology;Corneal thickness;

Countries

China

Contacts

Public Contactchunlin,liu

West China Hospital,Sichuan University

hxlcyjglb@163.com+86 189 8060 1740

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026