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Effects of remimazolam combined with afentanyl hydrochloride on hemodynamics during anesthesia induction in children with congenital heart disease

Effects of remimazolam combined with afentanyl hydrochloride on hemodynamics during anesthesia induction in children with congenital heart disease

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081101
Enrollment
Unknown
Registered
2024-02-22
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease

Interventions

Group RA:Remiazolam and alfentanyl were used during induction.
Group PS:Propofol and sufentanil were used during induction.

Sponsors

Shanghai Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 6 Years

Inclusion criteria

Inclusion criteria: children aged from 2 to 6 years old, regardless of gender; children with congenital heart disease who need elective congenital heart disease correction (mainly left-to-right shunt); American College of Anesthesiologists (American Society of Anesthesiologists,ASA) grade II~IV; the guardian of the child voluntarily signed the informed consent form;

Exclusion criteria

Exclusion criteria: emergency surgery; history of allergy to experimental drugs; severe organic diseases before operation; vasoactive drugs used before operation; children and their guardians refused to participate in the study

Design outcomes

Secondary

MeasureTime frame
Choking reflex;Disappearance time of eyelash reflex;success rate of induction;Injection pain;

Primary

MeasureTime frame
Incidence of hypotension;

Countries

China

Contacts

Public ContactZheng Jijian

Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine

zhengjijian@scmc.com.cn+86 189 6485 3803

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026