Acute generalized exanthematous pustulosis
Conditions
Interventions
Cyclosporine group:Oral cyclosporine (3mg/kg/d ,q12h,5day 1.5mg/kg/d,q12h,2day)
Hormone groupv:The method of intravenous infusion is to use 1mg/kg of methylprednisolone sodium succinate daily
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1: AGEP (Euro SCAR score = 8) patients with typical clinical manifestations who require hospitalization and are aged = 18 years old 2: Voluntary participation, patients or family members can sign informed consent forms, and patients can receive treatment and follow-up as required.
Exclusion criteria
Exclusion criteria: 1: Individuals who are allergic or intolerant to the drugs observed in this experiment 2: Severe liver and kidney dysfunction, uncontrolled hypertension or infection 3: Individuals with mental illness, epilepsy, or severe endocrine disorders 4: Pregnant or lactating women, or women preparing for pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine and biochemistry;Erythema resolution time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of first symptom improvement, length of hospital stay, and cessation of pustule formation after; | — |
Countries
China
Contacts
Public ContactChuan Wan
The First Affiliated Hospital, Jiangxi Medical College, Nanchang University
Outcome results
None listed