Crohn's disease
Conditions
Interventions
Normal diet group:Gradual resumption of normal diet on the fifth postoperative day (refer to CD Postoperative Dietary Management)
Nutritional powder group:In the nutrition powder group, patients began to take total enteral nutrition orally gradually from the fifth day after surgery for eight weeks.
Sponsors
Department of Colorectal Surgery, Zhongnan Hospital, Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Subjects must meet all of the following conditions to enter the trial. (1) CD patients undergoing elective partial enterectomy and anastomosis (fibrous main stenosis with proximal intestinal dilatation, enterocutaneous fistula, enterocutaneous fistula with intestinal stenosis, abscess or cellulitis); (2) CD was suspected before operation, and the postoperative pathology was consistent with the change of CD; (3) Age 18-65 years old; (4) The patient agrees to participate in the study and signs the informed consent.
Exclusion criteria
Exclusion criteria: Subjects must exclude all of the following conditions to enter the study. (1) Emergency surgery; (2) intolerance of enteral nutrition; (3) Total enteral nutrition was used for less than 4 weeks; (4) Have participated in other clinical studies; (5) multiple organ dysfunction; (6) Have a history of thoracic and abdominal surgery, such as esophageal cancer, gastric cancer, etc.; (7) Combined with other diseases affecting digestive tract absorption, such as short bowel syndrome, cirrhosis, ankylosing spondylitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endoscopic recurrence rate and surgical recurrence rate at 1 year after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative complications in both groups;Compare the difficulty of surgery between two groups;improvement of lesion area;resection of lesion segment area;Body Mass Index;serum albumin;Serum C-reactive protein; | — |
Countries
China
Contacts
Public ContactDing Zhao
Department of Colorectal Surgery, Zhongnan Hospital, Wuhan University
Outcome results
None listed