Auditory Neuropathy
Conditions
Interventions
Experimental group :Anodal stimulation of transcranial direct current stimulation
Control group :Sham stimulation of transcranial direct current stimulation
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for subjects in the AN group were as follows: 1) Age 18~40 years old, head circumference 55~60cm, and healthy except for hearing problems; 2) Confirmed diagnosis of AN: severe abnormalities of auditory brainstem response; otoacoustic emissions can be elicited and contralateral suppression test fails; normal acoustic conductance tympanogram, loss of stapedial muscle reflex or elevated threshold; abnormal cochlea electrogram-SP/AP ratio; normal pure tone audiometry or mild to severe hearing loss; disproportionate decrease in speech recognition rate and pure tone hearing and the speech recognition rate is >12%. 3) Subjects or those who have signed an informed consent form by an authorized relative of the subject. The inclusion criteria for normal hearing subjects were as follows: 1) Age and gender matched to the AN group, with a head circumference of 55-60 cm; 2) Normal hearing and good health.
Exclusion criteria
Exclusion criteria: Exclusion criteria for subjects in the AN group were as follows: 1) Exclusion of cognitive dysfunction; 2) Comorbid severe neurological disorders; 3) Diagnosis of syndromic type diseases; 4) Implantation of metal and electronic devices in the body; 5) Participation in other clinical trials within 3 months; 6) Those with bleeding tendency or coagulation disorder; 7) Those who are not suitable to wear the test instruments in the stimulated area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Speech recognition score; | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA Scale Score; | — |
Countries
China
Contacts
Public ContactQiuju Wang
Chinese PLA General Hospital
Outcome results
None listed