Orthopaedics
Conditions
Interventions
Group A:S (+) -ketamine was used during the perioperative period
Group C:S (+) -ketamine was not used during the perioperative period
Sponsors
Municipality Hospital of Jinjiang(Shanghai Sixth People's Hospital Fujian Hospital)
Eligibility
Sex/Gender
All
Age
3 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1.Age <= 17 years old 2.Elective orthopaedic surgery under general anesthesia 3.ASA?~? 4.The patient's guardian voluntarily signed an informed consent form
Exclusion criteria
Exclusion criteria: 1: 1.The expected length of stay was less than 48 hours 2.Patients expected to enter the ICU postoperatively 3.The patient was expected to return to the ward with a tracheal catheter 4.Allergic to the active ingredients or excipients of S (+) -ketamine 5.Severe disturbance of consciousness or psychosis or Cognitive impairment 6.Congenital heart defect and the growth is seriously backward children 7.Patients with contraindications to the use of S (+) -ketamine injection 1) High intracranial pressure 2)High intraocular pressure,Glaucoma,Penetrating ocular trauma 3)High blood pressure 4)Hyperthyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FLACC pain score;Opioid dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first salvage analgesic use after surgery;Incidence of salvage analgesia within 48 hours after surgery;Time of anesthesia recovery;Incidence of delirium in awakening period;Incidence of intraoperative adverse events;Incidence of postoperative adverse events;Pharmacoeconomic indicators; | — |
Countries
china
Contacts
Public ContactLIN Jianshui
Municipality Hospital of Jinjiang(Shanghai Sixth People's Hospital Fujian Hospital)
Outcome results
None listed