depressive disorder
Conditions
Interventions
HD-tDCS+rTMS group:On the basis of drugs, HD-tDCS and rTMS was given
HD-tDCS group:On the basis of drugs, HD-tDCS was given
rTMS group:On the basis of drugs, rTMS was given
Conventional drug group:Only medication is given, no physical intervention is applied
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60, Han nationality; 2. Meet the DSM-V diagnostic criteria for depressive disorder, either first or recurrent; 3. HAMD-17 scores =17 in screening period and baseline period; 4. Able to understand all questionnaires in this study; 5.Volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with serious physical or neurological diseases; 2. A history of exposure to psychoactive substances or other mental illness; 3. There are metal objects in the body (such as metal dentures, cardiac pacemakers, etc.) affecting the MRI examination; 4. History of coma and epilepsy; 5. Severe suicidal tendencies or severe excitability; 6. Pregnant or lactating women; 7. Patients who have received tDCS/rTMS/ECT treatment within the last 6 months.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory, BDI;Snaith-Hamilton Pleasure Scale, SHAPS;Magnetic resonance imaging, MRI;functional near-infrared spectroscopy, fNIRS; | — |
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale, HAMD-17;The Chinese Brief Cognitive Test, C-BCT;electroencephalogram, EEG; | — |
Countries
China
Contacts
Public ContactZhaohui Zhang
The First Affiliated Hospital of Xinxiang Medical University
Outcome results
None listed