Rheumatoid arthritis
Conditions
Interventions
Therapeutic effect response group/ Non responsive treatment group :None
Sponsors
The University of Hong Kong-Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.age =18 years old; 2.comply with 1987 ACR standard or 2010 ACR/EULAR RA classification standard 3. Moderate-to-severe disease activity: DAS28 or SDAI or CDAI assessed RA to achieve moderate-to-severe activity 4. combination of drugs: combined use of traditional synthetic disease-modifying antirheumatic drugs (csDMARDs), including hydroxychloroquine (HCQ), methotrexate (MTX), leflunomide (LEF), salazosulfopyridine (SSZ), Eramod (IGU), etc.
Exclusion criteria
Exclusion criteria: 1. Combined with other types of inflammatory rheumatism and musculoskeletal diseases; 2. Currently suffering from malignant tumor or infection that may affect the level of serum inflammatory factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DAS-28;CDAI;ACR20 response;Serum inflammatory factor levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| SDAI;ACR50/70 response;Adverse event ;Serious adverse event; | — |
Countries
China
Contacts
Public ContactJinxian Huang
The University of Hong Kong-Shenzhen Hospital
Outcome results
None listed