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Intervention Research and Product Transformation Exploration of Tibetan Medicinal Plant Active Ingredients in Nasal Mucosal Inflammatory Diseases

Intervention Research and Product Transformation Exploration of Tibetan Medicinal Plant Active Ingredients in Nasal Mucosal Inflammatory Diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080992
Enrollment
Unknown
Registered
2024-02-20
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis, chronic sinusitis

Interventions

Saffron treatment group:The saffron treatment group adopts the recommended treatment guidelines+saffron physiological saline extract nasal spray
Jinkui treatment group:Recommended treatment for the Jinkui treatment group using guidelines+Jinkui physiological saline extract nasal spray
control group:The control group received treatment recommended by the guidelines

Sponsors

People's Hospital of Tibet Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: (1) Those who meet the diagnostic criteria of the "Guidelines for the Diagnosis and Treatment of Chronic Nasosinusitis in China (2018)" or "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis"; (2) The patient is aged between 18 and 60 years old;

Exclusion criteria

Exclusion criteria: (1) Women in special periods such as pregnancy and lactation; (2) Patients with severe underlying diseases, such as cardiovascular, liver, and kidney diseases; (3) Patients with mental disorders, anxiety disorders, and other diseases; (4) Those who have received immunotherapy, anti infection, hormone therapy, etc. within the past month; (5) Patients with chronic paranasal sinusitis or organic lesions of the nasal cavity, or those undergoing nasal surgery; (6) Contraindications to saffron extract and sunflower extract components; (7) Those who have taken medication related to treatment within the past 2 weeks; (8) Disagree to participate in this study.

Design outcomes

Primary

MeasureTime frame
Nasal and Sinus Outcome Test 22 Score (SNOT-22);

Secondary

MeasureTime frame
Symptom Visual Analog Scale;Lund Kennedy score for nasal endoscopy;Immunoinflammatory cytokines;

Countries

People's Republic of China

Contacts

Public ContactLuo Ba

People's Hospital of Tibet Autonomous Region

bhanor@163.com+86 139 0890 1135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026