Allergic rhinitis, chronic sinusitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Those who meet the diagnostic criteria of the "Guidelines for the Diagnosis and Treatment of Chronic Nasosinusitis in China (2018)" or "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis"; (2) The patient is aged between 18 and 60 years old;
Exclusion criteria
Exclusion criteria: (1) Women in special periods such as pregnancy and lactation; (2) Patients with severe underlying diseases, such as cardiovascular, liver, and kidney diseases; (3) Patients with mental disorders, anxiety disorders, and other diseases; (4) Those who have received immunotherapy, anti infection, hormone therapy, etc. within the past month; (5) Patients with chronic paranasal sinusitis or organic lesions of the nasal cavity, or those undergoing nasal surgery; (6) Contraindications to saffron extract and sunflower extract components; (7) Those who have taken medication related to treatment within the past 2 weeks; (8) Disagree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal and Sinus Outcome Test 22 Score (SNOT-22); | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom Visual Analog Scale;Lund Kennedy score for nasal endoscopy;Immunoinflammatory cytokines; | — |
Countries
People's Republic of China
Contacts
People's Hospital of Tibet Autonomous Region