Acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1). Those who meet the diagnostic criteria for acute pancreatitis and the differentiation criteria for spleen and stomach weakness in traditional Chinese medicine. (2). Be between 18 and 70 years old, and have no gender limit. (3). Acute onset, admission within 72 hours after the appearance of typical abdominal symptoms. (4). No nutritional support before admission; (5). Patients with nasal jejunal nutrition and enteral nutrition (6). Symptoms of enteral nutritional intolerance (7). Intestinal sounds 10 times/min (8). Enteral nutrition tolerance score [38]: =3 points (9). Informed consent, voluntary testing. The process of obtaining informed consent should comply with GCP regulations.
Exclusion criteria
Exclusion criteria: (1). Pancreatitis of pregnancy; (2). Autoimmune pancreatitis (3). Patients with gastrointestinal tumors and surgery (4). Combined with multiple organ failure, need ventilator treatment (5). Pregnant and lactating women. (6). Those who cannot give full informed consent due to intellectual or behavioral disabilities. (7). Suspected or confirmed history of alcohol and drug abuse. (8). According to the judgment of the investigator, other lesions that reduce the possibility of enrollment or complicate enrollment, such as frequent changes in the working environment, are likely to cause loss to follow-up. (9). Allergic constitution, such as a history of allergy to two or more drugs or foods; or known to be allergic to the ingredients of this drug. (10). Fever patients. (11). Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Harvest the target energy (25kcal/(kg·d) to reach the time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Actual daily nutrient intake;Abdominal circumference;Severity of the disease;weight;BMI index;Water content, muscle mass;Enteral nutritional intolerance score;Fluctuations in bowel sounds; serum interleukin-6; hypersensitivity C-reactive protein;Serum albumin;Serum pre-albumin ;haemoglobin; | — |
Countries
China
Contacts
Jiangsu Provincial Hospital of Traditional Chinese Medicine