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MiR-143, Transforming Growth Factor- ß Analysis of the predictive value of the expression of inflammatory factors on the progression of acute respiratory distress syndrome in patients

MiR-143, Transforming Growth Factor- ß Analysis of the predictive value of the expression of inflammatory factors on the progression of acute respiratory distress syndrome in patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080934
Enrollment
Unknown
Registered
2024-02-18
Start date
2024-01-02
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute respiratory distress syndrome

Interventions

Mild ARDS patients:Non invasive mechanical ventilation treatment
Moderate ARDS patients:Lung protective ventilation and treatment of lung atelectasis
Severe ARDS patients:Lung protective ventilation and treatment of lung atelectasis

Sponsors

Hai'an People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ARDS patients who meet the 2012 Berlin standards voluntarily sign an informed consent form to enter the study.

Exclusion criteria

Exclusion criteria: ? Severe chronic related diseases that affect the lungs, such as bronchial asthma, bronchiectasis, interstitial lung disease, chronic obstructive pulmonary disease, pulmonary heart disease, etc.; ? Chronic renal insufficiency; ? Acute myocardial ischemia or severe arrhythmia; ? Pulmonary artery embolism; ? Pregnancy; ? Patients with rheumatism and long-term hormone use.

Design outcomes

Primary

MeasureTime frame
miRNA-143;transforming growth factor-ß;C-reactive protein;procalcitonin;Interleukin-6;Interleukin-8;tumor necrosis factor-a;

Secondary

MeasureTime frame
acute physiology and chronic health evaluation scoring systemII;Lung Injury Score;Sequential Organ Failure Assessment;Pulse indicator Continous Cadiac Output;Mechanical ventilation time;ICU hospitalization time;case fatality rate;

Countries

China

Contacts

Public ContactZunguo Pu

Hai'an People's Hospital

pzgsci@163.com+86 139 1285 5289

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026