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Effect of intravenous subanesthesic dose of Esketamine on pain,mood and early recovery after cesarean section.

Effect of intravenous subanesthesic dose of Esketamine on pain,mood and early recovery after cesarean section.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080929
Enrollment
Unknown
Registered
2024-02-18
Start date
2023-11-24
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute postoperative pain, postpartum depression

Interventions

Group ESS:Esketamine 0.25 mg/kg

Sponsors

Cangzhou Central Hosptial
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: (1)Gestation =37 weeks (2)Age: 20 ~ 35 years old (3)ASA ?-? (4)Monocyesis (5)Puerpera cesarean section under subarachnoid anesthesia

Exclusion criteria

Exclusion criteria: (1)It has contraindications to subarachnoid anesthesia (2)Allergic to esketamine or bupivacaine (3)Placenta previa complete (4)Severe placental abruption (5)Severe preeclampsia (6)Pregnancy with chronic hypertension (7)Chronic hypertension with preeclampsia (8)Fetal distress or abnormality (9)History of anxiety or depression (10)Previous insomnia (11)Severe liver and kidney dysfunction

Design outcomes

Primary

MeasureTime frame
numerical rating scale,NRS;

Secondary

MeasureTime frame
The amount of opioid used;Number of effective compressions of analgesic pump;Number of remedial analgesia;Richards-Campbell Sleep Questionnaire,RCSQ;40-item quality of recovery (QoR-40) questionnaire;Self-Rating Anxiety Scale,SAS;Self-rating depression scale,SDS;Maternal satisfaction with labor analgesia;Recovery time of gastrointestinal function;The first time to get out of bed after delivery;

Countries

China

Contacts

Public ContactWenbo Sun

Cangzhou Central Hosptial

15103172838@139.com+86 151 0317 2838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026