bile duct stones
Conditions
Interventions
remimazolam group:remimazolam group were intravenously administered with 0.2 mg/kg of remimazolam tosylate. The initiation of endoscopy treatment commenced when the modified observer assessment of th
propofol group:propofol group received an intravenous injection of 1.5 mg/kg of propofol emulsion injection, and the initiation of endoscopy treatment occurred when the modified observer's assessment
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Patients with a confirmed diagnosis of biliary and pancreatic disease; (2) All patients requiring ERCP surgery with corresponding indications for surgical treatment; (3) Patients categorized as ASA grade I or II; (4) Patients with no contraindications or allergic reactions to remimazolam tosylate, propofol, and other anesthetic drugs; (5) Informed consent was obtained from patients participating in this study; (6) Ethical approval was obtained for the implementation of the research protocol.
Exclusion criteria
Exclusion criteria: (1) Patients with severe cardiovascular or neurological disease; (2) Patients with contraindications to surgery; (3) Patients with known allergies to benzodiazepines and opioids, and patients with prolonged use of such drugs; (4) Patients with severely abnormal liver and kidney function; (5) Patients with incomplete data collection of observation indicators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| induction time;Hemodynamic Indicator Comparison(Heart rate, Mean Arterial Pressure);Number of first induction success;Recovery time;Number of additional sedatives;adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stress Response Index(Adrenaline, Norepinephrine,Cortisol); | — |
Countries
China
Contacts
Public ContactYongmei Sun
Shandong Provincial Third Hospital
Outcome results
None listed