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Efficacy Study of Tube Feeding Compared to Nutritional Education and Dietary Guidance in Radical Radiotherapy Patients with Esophageal Malignant Tumors: A Prospective, Multicenter, Parallel, Randomized, Open-Label, Controlled Study

Efficacy Study of Tube Feeding Compared to Nutritional Education and Dietary Guidance in Radical Radiotherapy Patients with Esophageal Malignant Tumors: A Prospective, Multicenter, Parallel, Randomized, Open-Label, Controlled Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080914
Enrollment
Unknown
Registered
2024-02-18
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carcinoma of esophagus

Interventions

Experimental group:Prophylactic nasal feeding tube
Control group:None

Sponsors

Taizhou Tumor Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age =18 years old; (2) Pathological diagnosis of esophageal malignancy; (3) can eat normally through the mouth; (4) Radical radiotherapy or radical concurrent chemoradiotherapy; (5) ECOG score 0-2; (6) Complete clinical data before radiotherapy: age, gender, ECOG score, height, weight, lymphocyte subsets, CRP, biochemistry and blood routine, etc.; (7) There must be at least one measurable evaluable lesion that meets the RECIST1.1 criteria.

Exclusion criteria

Exclusion criteria: (1) Patients with mental disorders; (2) Patients with severe cardiopulmonary dysfunction; (3) Other malignant tumors coexist; (4) had previously received radiotherapy; (5) Combined with other related diseases: such as other nutrient absorption disorders, metabolic abnormalities and other diseases.

Design outcomes

Primary

MeasureTime frame
Overall survival;

Secondary

MeasureTime frame
ECOG score;Classification of radiation damage;Progression free survival;Therapeutic response;

Countries

China

Contacts

Public ContactLin Zheng

Department of Radiation Oncology, Taizhou Tumor Hospital

y215180575@zju.edu.cn+86 152 5860 2261

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026