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The Median Effective Doses of Ciprofol Combined with Sufentanil for Suppressing the Laryngeal Mask Airway Insertion Response in Young and Elderly Patients

The Median Effective Doses of Ciprofol Combined with Sufentanil for Suppressing the Laryngeal Mask Airway Insertion Response in Young and Elderly Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080891
Enrollment
Unknown
Registered
2024-02-17
Start date
2024-02-17
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngeal mask implantation reaction

Interventions

Youth group:According to the plan, the first dose of Ciprofol injection was set at 0.4mg/kg, and the dose of Ciprofol in the next patient was determined according to whether there was a laryngeal mas
Older adults group:According to the plan, the first dose of Ciprofol injection was set at 0.4mg/kg, and the dose of Ciprofol in the next patient was determined according to whether there was a laryng

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: ? The study includes elective laryngeal mask general anesthesia patients, regardless of gender, aged between 18-44 years and 60-79 years; ? Patients classified as ASA (American Society of Anesthesiologists) physical status I—III; ? Patients who agree to sign an informed consent form.

Exclusion criteria

Exclusion criteria: ? Baseline measurements upon entering the room: systolic blood pressure >160mmHg or diastolic blood pressure >100mmHg, heart rate 100bpm. ? Acute respiratory infection, acute exacerbation of COPD, poorly controlled asthma. ? Mental disorders including schizophrenia, depression, cognitive impairment, etc. ? Allergy to study drugs. ? Patients who have taken benzodiazepines in the past three months. ? Pregnant or breastfeeding women. ? Patients anticipated to have difficult airways. ? Body Mass Index (BMI) less than 19 kg/m² or greater than 28 kg/m². ? Severe comorbidities (including but not limited to renal failure, liver failure, cerebrovascular accidents, heart failure, myocardial infarction, etc.)

Design outcomes

Primary

MeasureTime frame
ED50;

Secondary

MeasureTime frame
ED95;Adverse reaction;Laryngeal mask implantation reaction;

Countries

China

Contacts

Public Contactlilinji

Nanchong Central Hospital

llj-stephen@163.com+86 155 8300 9555

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026