Depression and pain after cesarean section
Conditions
Interventions
Esketamine Group (S Group):After delivery, 0.25mg/kg esketamine was given after umbilical cord blood was ligation
Control Group(C Group):After the birth of the newborn, the umbilical cord blood was ligation and the same dose of normal saline was given about 5ml
Sponsors
Yongchuan Hospital affiliated to Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Full-term pregnant women aged 18-40 years, (2) No history of depression before or during pregnancy, no family history of depression, (3) Body mass index (BMI) =30Kg/m2, (4) Willing to cooperate and sign consent form, and (5) ASA grade I-II.
Exclusion criteria
Exclusion criteria: 1 Pregnant women with a history of depression or depressive symptoms before birth; 2 Preterm birth or less than a month of maternity; 3 Body mass index >30kg/m2; 4. Pregnant women with serious obstetric diseases or with vital organ diseases before delivery; 5. Pregnant women or pregnant women with thyroid insufficiency or severe anemia; 6 Pregnant women allergic to esketamine; 7. Mothers who are unwilling to cooperate and refuse to sign the consent form; 8 Women who had been included in other studies, 9 Women with multiple pregnancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postnatal depression;Postoperative Pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| The dosage of postoperative analgesics in each group;The occurrence of related complications; | — |
Countries
China
Contacts
Public ContactXiangqian Wan
Yongchuan Hospital affiliated to Chongqing Medical University
Outcome results
None listed