Atypical endometrium hyperplasia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) For patients proved to be Atypical endometrial hyperplasia (AEH) by diagnostic curettage pathology, the patients had fertility requirements and required to retain fertility function, or had no fertility requirements but were < 45 years old and strongly required to retain fertility function. The atypical endometrial hyperplasia was atypical. 2) Body mass index (BMI) =24. 3) No contraindications to the use of progesterone, no adnexal tumors, breast tumors and other oncologic diseases. 4) Good compliance, timely follow-up and regular pathological examination. 5) Have been treated in the endometrial lesion department of our hospital and have understood and signed the informed consent for the care and treatment of endometrial atypical hyperplasia. (Endometrial dysplasia has the risk of potential malignancy and progression to endometrial cancer, and the proportion of patients with AEH diagnosed by biopsy and pathology is as high as 19% to 45%. Prior to conservative treatment, the informed consent for nursery treatment is signed, and it is understood that conservative treatment has a certain recurrence rate. Once fertility preservation is abandoned, surgical resection of the uterus can be considered.) 6) Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Complicated with serious diseases of the blood system, abnormal liver and kidney function, autoimmune diseases, etc. 2) Patients with other malignant tumors of the reproductive system and hereditary tumors of the reproductive system in the family; 3) Patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system and mental illness. 4) People who are allergic to multiple drugs or have a known history of "needle sickness".
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| weight;waistline;body composition; | — |
Primary
| Measure | Time frame |
|---|---|
| Endometrial pathology; | — |
Countries
China
Contacts
Obstetrics and Gynecology Hospital of Fudan University