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Clinical efficacy of acupoint catenary embedding combined with progesterone in the treatment of obese endometrial atypical hyperplasia

Clinical efficacy of acupoint catenary embedding combined with progesterone in the treatment of obese endometrial atypical hyperplasia

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080879
Enrollment
Unknown
Registered
2024-02-13
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atypical endometrium hyperplasia

Interventions

Treatment group (acupuncture point embedding combined with progesterone):acupoint thread-embedding therapy
Control group (progesterone treatment):Chinese consensus on diagnosis and treatment of endometrial hyperplasia [6] Recommended nursing treatment plan

Sponsors

Obstetrics and Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1) For patients proved to be Atypical endometrial hyperplasia (AEH) by diagnostic curettage pathology, the patients had fertility requirements and required to retain fertility function, or had no fertility requirements but were < 45 years old and strongly required to retain fertility function. The atypical endometrial hyperplasia was atypical. 2) Body mass index (BMI) =24. 3) No contraindications to the use of progesterone, no adnexal tumors, breast tumors and other oncologic diseases. 4) Good compliance, timely follow-up and regular pathological examination. 5) Have been treated in the endometrial lesion department of our hospital and have understood and signed the informed consent for the care and treatment of endometrial atypical hyperplasia. (Endometrial dysplasia has the risk of potential malignancy and progression to endometrial cancer, and the proportion of patients with AEH diagnosed by biopsy and pathology is as high as 19% to 45%. Prior to conservative treatment, the informed consent for nursery treatment is signed, and it is understood that conservative treatment has a certain recurrence rate. Once fertility preservation is abandoned, surgical resection of the uterus can be considered.) 6) Voluntarily participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Complicated with serious diseases of the blood system, abnormal liver and kidney function, autoimmune diseases, etc. 2) Patients with other malignant tumors of the reproductive system and hereditary tumors of the reproductive system in the family; 3) Patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system and mental illness. 4) People who are allergic to multiple drugs or have a known history of "needle sickness".

Design outcomes

Secondary

MeasureTime frame
weight;waistline;body composition;

Primary

MeasureTime frame
Endometrial pathology;

Countries

China

Contacts

Public ContactMinjie Tang

Obstetrics and Gynecology Hospital of Fudan University

tangminjie7095@fckyy.org.cn+86 186 1663 0230

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026