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Effect of transcranial magnetic stimulation combined with extracorporeal shockwave therapy for post-stroke spasticity

Effect of transcranial magnetic stimulation combined with extracorporeal shockwave therapy for post-stroke spasticity

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080862
Enrollment
Unknown
Registered
2024-02-09
Start date
2024-02-18
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Experimental group 1:Routine rehabilitation combined with TMS
Experimental group 2:Routine rehabilitation combined with ESWT
Experimental group 3:Routine rehabilitation combined with TMS and ESWT
Control group:Routine rehabilitation

Sponsors

Army Medical Center of PLA (Daping hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1: Patients with stroke (cerebral infarction or cerebral hemorrhage) diagnosed with hemiplegia on one side of the limb, in accordance with the diagnostic criteria established by the 4th Academic Conference on Cerebrovascular Diseases of the Chinese Medical Association, confirmed by CT and/or MRI and it is the first onset 2: MAS score =1 3: Clear awareness, good cognitive function, and ability to cooperate in completing evaluations and treatments 4: The selected patients are all under the age of 80 and voluntarily sign an informed consent form 5: Vital signs are stable and neurological symptoms no longer progress 6: No serious heart disease, renal insufficiency, malignant tumors or other critical illnesses

Exclusion criteria

Exclusion criteria: 1: The condition deteriorates with new infarcts or bleeding 2: The patient has contraindications for TMS or ESWT such as intracranial metal implants or history of epilepsy 3: Patients suffer from liver and kidney dysfunction, malignant tumors, congestive heart failure, multiple organ failure, and other diseases

Design outcomes

Primary

MeasureTime frame
Modified Ashworth scale;

Secondary

MeasureTime frame
Modified Tardieu scale;Fugl-Meyer assessment scale;Berg balance scale;Modified Barthel index;Range of motion;Stroke specific quality of life scale;F wave;H-reflex;T-reflex;Cortical excitability;Oxyhemoglobin;Reduced hemoglobin;

Countries

China

Contacts

Public ContactChang-Yue Gao

Army Medical Center of PLA (Daping hospital)

gaochangyue1990@163.com+86 23 6874 6181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026