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Evaluation of long term effect of LKP or PKP in treatment of macular corneal dystrophy: A multicenter retrospective cohort study

Evaluation of long term effect of LKP or PKP in treatment of macular corneal dystrophy: A multicenter retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080851
Enrollment
Unknown
Registered
2024-02-09
Start date
2024-02-15
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular corneal dystrophy

Interventions

LKP group (The patient underwent lamellar keratoplasty):None
PKP group (The patient underwent penetrating keratoplasty):None

Sponsors

Qingdao Eye Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: A. Clear diagnosis of macular corneal dystrophy; B. Patients who received first LKP or PKP in sub research centers; C. Follow up time = 1 year; D. Patients who had a follow-up time of less than 1 year but experienced graft failure within 1 year after surgery were also included in this study.

Exclusion criteria

Exclusion criteria: A. Excluding patients with concomitant other corneal diseases; B. Exclude patients who have been diagnosed with diseases of the retina, choroid, and optic nerve before surgery; C. Exclude patients diagnosed with glaucoma before surgery; D. Exclude patients who cannot provide anterior segment photos for confirmed diagnosis.

Design outcomes

Primary

MeasureTime frame
visual acuity;graft survival time;

Secondary

MeasureTime frame
The reasons for graft failure;Time without recurrence;corneal endothelium;Intraoperative and postoperative complications;The proportion, causes, and surgical methods of patients undergoing multiple surgeries;The impact on the life-style and economic well-being of patients;

Countries

China

Contacts

Public ContactLixin Xie

Qingdao Eye Hospital of Shandong First Medical University

alice.567@163.com+86 139 0639 6863

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026