Comparison of sedative effects of midazolam and dexmedetomidine in outpatient dental surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400080818

Enrollment

Unknown

Registered

2024-02-07

Start date

2024-02-18

Completion date

Unknown

Last updated

2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental diseases

Interventions

Group Midazolam:This group of patients received intravenous injection of 0.07-0.1mg/kg midazolam

Group Dexmedetomidine:This group of patients received 1ug/kg dexmedetomidine nasal drops

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) ASA Level I or II (2) Stomatologists evaluate patients who can undergo surgery in outpatient settings (3) Age 18-85 years old (4) BMI = 35kg/m2 (5) Patient cooperation

Exclusion criteria

Exclusion criteria: (1) Serious circulatory, respiratory, and endocrine system diseases exist (2) Previous history of allergy to local anesthetics (3) There are contraindications to sedative drugs (4) History of addiction or abuse of sedative drugs (5) Pregnant and lactating women (6) Patients and their families are unwilling to sign the informed consent form or cannot follow the research procedure

Design outcomes

Primary

Measure	Time frame
Sedation score;	—

Secondary

Measure	Time frame
heart rate;blood pressure;Blood oxygen saturation;Adverse reactions;	—

Countries

China

Contacts

Public ContactJingmei Yang

Chinese People's Liberation Army 63750 Hospital

yangjingmei0119@163.com+86 180 9133 6383

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026