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Observation on the effect of Butorphanol combined with Tropisetron in the prevention of adverse reactions to Hemabate during caesarean section

Observation on the effect of Butorphanol combined with Tropisetron in the prevention of adverse reactions to Hemabate during caesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080814
Enrollment
Unknown
Registered
2024-02-07
Start date
2024-02-15
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Group B+T:None

Sponsors

Qingdao Women and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 20-45 years old, weight 55-90 kg, gestational week 37-41 weeks, cardiac function grade I-II, American Society of Anesthesiologists (ASA) classification grade II, blood routine, bleeding and coagulation tests were normal, and liver and renal function tests were within normal values. Patients with elective cesarean section, anaesthesia by combined lumbar and epidural anaesthesia (CSEA) with intraoperative application of hemabate followed by butorphanol and tropisetron.

Exclusion criteria

Exclusion criteria: Patients with combined lumbar and rigid anaesthesia diffusion level lower than T6; intraoperative use of other opioids, sedative drugs, antiemetics, etc.; intraoperative application of more than 1 unit of hemabate; and patients with a BMI = 35 kg/m2.

Design outcomes

Primary

MeasureTime frame
Incidence of nausea and vomiting;

Secondary

MeasureTime frame
Incidence of chest tightness;Incidence of facial flushing;Incidence of hypoxemia;Incidence of excessive sweating;Incidence of chills;

Countries

China

Contacts

Public ContactHaiqing Zhang

Qingdao Women and Children's Hospital

wmm1107@sina.com+86 185 5326 3636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026