Sepsis-associated acute respiratory failure syndrome
Conditions
Interventions
sepsis -non-ARDS:not applicable
ARDS- light:not applicable
ARDS-medium:not applicable
ARDS-heavy:not applicable
Sponsors
Tianjin First Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1: age=18 years 2: sepsis 3: An artificial airway (endotracheal intubation, tracheotomy) has been established 4: require bronchoscopy or treatment
Exclusion criteria
Exclusion criteria: 1: Patients with malignant tumors 2: Patients with autoimmune disease or immunodeficiency 3: The patients were complicated with pneumothorax, bronchopleural fistula, severe pulmonary fibrosis and other severe pulmonary structural diseases 4: Patients with chronic heart failure 5: Patients during pregnancy 6: Long-term use of immunosuppressants in patients 7: Long-term hospitalized patients (=7 days) 8: The expected survival time is less than 48 hours 9: Patients who participated in other studies within 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differential protein;Differential metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of exosome surface markers;Acute Physioloy and Chronic Health Evaluation, APACHE ?;Sequential Organ Failure Assessment, SOFA; | — |
Countries
China
Contacts
Public ContactHua Xu
Tianjin First Center Hospital
Outcome results
None listed