Construction of a prediction model for anesthesia depth and nociceptive stimulation based on EEG in adult: the CONCEPT phase I clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400080797

Enrollment

Unknown

Registered

2024-02-07

Start date

2024-02-08

Completion date

Unknown

Last updated

2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia depth and nociceptive stimulation

Interventions

Sevoflurane(S) group:NA

Propofol(P) group:NA

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-65 years old, undergoing elective non-cardiac surgery under general anesthesia; (2) Sign informed consent; (3) ASA I-III level; (4) The expected anesthesia time (defined as the time from induction to cessation of anesthetics) is greater than 30 minutes.

Exclusion criteria

Exclusion criteria: (1) History of mental or neurological diseases such as autism, attention deficit hyperactivity disorder, epilepsy, and cerebral infarction, etc; (2) History of neurological surgery; (3) High risk of reflux aspiration who requires rapid sequential induction; (4) History of alcohol, opioid, sedative, or other psychotropic drug abuse; (5) Hearing, communication, physical movement or intellectual disabilities; (6) The EEG monitoring site conflicts with the surgical disinfection site; (7) Allergy to drugs or sensors used in the trial.

Design outcomes

Primary

Measure	Time frame
EEG features related to different levels of consciousness;EEG features related to nociceptive stimulation;	—

Secondary

Measure	Time frame
EEG features related to different anesthetics;	—

Countries

China

Contacts

Public ContactYuyi Zhao

West China Hospital, Sichuan University

zhaoyuyi@wchscu.cn+86 189 8060 6837

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026