none
Conditions
Interventions
Experimental group:Phlegm expectoration treatment was performed three times with an interval of more than 4 hours between treatments. Each treatment consisted of 6 groups, with 6 coughs in each group.
mode set to "automatic"
daytime cycle set at 15-30 minutes, and nighttime cycle set at 60-120 minutes, with a cough count set at 10 times.
Note: Daytime refers to the period from 30 minutes after the first treatment to befo
Control group:Phlegm expectoration treatment was performed three times with an interval of more than 4 hours between treatments. Each treatment consisted of 6 groups, with 6 coughs in each group. The
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old, gender is not limited; 2. Establishment of artificial airway (endotracheal intubation or tracheotomy) with the expectation of mechanical ventilation for at least 24 hours; 3. The estimated amount of expectoration in the 24 hours before enrollment is = 10ml; 4. The subject or his/her legal representative has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.History of bullous emphysema, pneumothorax, or mediastinal emphysema without appropriate drainage; 2.Chest trauma or surgery within the past month; 3.History of acute cerebral hemorrhage within the past two weeks; 4.Acute myocardial infarction or heart function grade IV within the past two weeks; 5.Uncorrected hypotension, with systolic blood pressure persistently below 90 mmHg despite appropriate treatment with vasopressors; 6.Uncontrolled malignant arrhythmias, including supraventricular tachycardia, ventricular tachycardia, ventricular fibrillation, and third-degree atrioventricular block; 7.Participation in any other clinical trials of drugs or medical devices within three months; 8.Other patients researchers believe are inappropriate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total amount of expectoration in 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of Blood Oxygen Saturation;Respiratory Mechanics Parameters;The evaluation of instrument performance; | — |
Countries
China
Contacts
Public ContactQingyuan Zhan
China-Japan Friendship Hospital
Outcome results
None listed